With this loss, Prajnesh lost a golden opportunity to face Djokovic in the second round.
If Prajnesh beats 144- ranked Ito, he could face World No. 2 Novak Djokovic in the second round.
India's World Group hopes are hanging by a slender thread as its top singles player, Somdev Devvarman is still doubtful to play Sunday's reverse singles in the play-off tie against Japan due to a shoulder injury.
India kept alive their hopes of staying in the elite Davis Cup World Group as Mahesh Bhupathi and Rohan Bopanna scored a hard-earned 7-5, 3-6, 6-3, 7-6 (3) win over Yuichi Sugita and Tatsuma Ito in the marathon doubles rubber in the play-off tie against Japan in Tokyo on Saturday.
Somdev Devvarman inched closer to a historic tennis gold at the Asian Games as the gritty Indian overcame a stunning second-set lapse to tame Tatsuma Ito and seal a place in the men's singles summit clash in Guangzhou, on Monday.
Tatsuma Ito and Michal Przysiezny claimed the biggest wins of their careers at the Japan Open on Tuesday when the local wildcard knocked out top seed Stan Wawrinka and the Polish qualifier saved match points to beat Jo-Wilfried Tsonga.
Naomi Osaka faces Zheng before possible meeting with Coco Gauff
It will be Prajnesh's fifth straight appearance in the main draw of a Grand Slam.
Indian players enjoyed a good day on the ATP Challenger tour as Yuki Bhambri reached the singles semifinals of the Traralgon event in Australia while Somdev Devvarman and Saketh Myneni reached the quarter-finals of the Charlottesville event in the United States.
Yuki Bhambri recovered well from a poor start to beat New Zealand's Michael Venus in a three-setter and advance to the singles quarter-finals of the ATP Challenger event in Traralgon, Australia.
India's struggling singles star Somdev Devvarman was handed a tough opener in the ATP Chennai Open as he is pitted against sixth seed and world number 38 Yen-Hsun Lu.
Novak Djokovic is chasing a record-extending eighth Australian Open title, while Dominic Thiem will bid to become the first man born in the 1990s to win a major title.
Serbia carved out a 2-0 lead over rivals Croatia while Britain led the US by the same score and holders Switzerland were tied with Belgium in the Davis Cup.
Ramkumar Ramanathan paid the price of not containing his unforced errors as he made a first round exit from the ATP Chennai Open while his compatriot and qualifier Vijay Sundar Prashanth also bowed out after a crushing defeat, on Tuesday.
Images from Day 3 of the Australian Open in Melbourne on Wednesday
India's Somdev Devvarman on Saturday bowed out of the Atlanta Tennis Championships singles event after a straight-set defeat at the hands of defending champion Mardy Fish of the United States in the quarter-finals.
Yuki Bhambri won his first ATP Challenger level singles title of the season and second of his career on Monday after humbling top seed American Bradely Klahn (ranked 123) in the rain-hit summit clash of the Traralgon event in Australia.
Spain's third seed Roberto Bautista Agut made a smooth entry into the men's quarter-finals at the ATP Chennai Open tennis tournament with a fluent 6-3, 6-2 win over German Peter Gojowczyk.
Roger Federer faced down local battler John Millman 4-6, 7-6(2), 6-4, 4-6, 7-6(8) in a five-set thriller on Friday night to reach the last 16 of the Australian Open. Defending champion Novak Djokovic thumped Japanese Yoshihito Nishioka 6-3, 6-2, 6-2 in the third round of the Australian Open on Friday to stay on course for a record-extending eighth title at Melbourne Park. Images from Day 5 of the 2020 Australian Open.
Images from Day 1 of the Australian Open in Melbourne on Monday.
IMAGES from the Australian Open on Tuesday.
India's Leander Paes and Rohan Bopanna crashed out of the Japan Open following a straight set defeat against Ivan Dodig and Marcelo Melo, in Tokyo on Thursday.
It was a day of surprises at Flushing Meadows in New York as seeded players were knocked out one after the other on Friday.
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